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How to use the database
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Video 1
How to consult information for one disease
Video 2
How to build a report for several diseases
Video 3
How to consult the prioritisation model
Video 4
How to consult the gap analysis
How to consult information for one disease
How to build a report for several diseases
How to consult the prioritisation model
How to consult the gap analysis
Step 1:
select diseases filters
Any
Epizootic diseases
Food producing animal complexes
Zoonotic diseases
Any
Cattle
Sheep/goat
Pig
Poultry
Horse
Dog/cat
Bee
Any
Europe
Americas
Africa & Middle East
Asia & Australasia
Global
African Horse Sickness
African Swine Fever
African Trypanosomiasis (scores for Non Tse-Tse transmitted)
Anthrax
Avian chlamydiosis (C. psittaci)
Avian Influenza
BHV-I (IBR)
Bluetongue
Bovine respiratory syncytial virus (BRSV)
Bovine Spongiform Encephalopathy
Bovine Tuberculosis
BRSV
Brucellosis (Gap analysis scoring for cattle brucellosis)
BVDV
Campylobacter
Classical Swine Fever
Coccidiosis (poultry)
Contagious agalactia
Contagious Bovine Pleuropneumonia
Coronaviruses in pigs
Coronaviruses in poultry
Crimean-Congo Haemorrhagic fever
Cryptosporidiosis
E. coli
Echinococcosis (scores for cystic Echinococcosis)
Environmental mastitis (E. coli, Str. uberis)
Epizootic haemorrhagic disease
Foot and Mouth Disease
Hepatitis E Virus
Leishmaniasis
Leptospirosis
Liver Fluke
Lumpy Skin Disease
Mycoplasma bovis
Nematodes
Nipah virus
Orthopox
Ovine chlamydiosis (C. Abortus)
Parapox
Paratuberculosis
PCV II
Peste des Petits Ruminants
Porcine cysticercosis
Poultry Red Mite
PRRS
Q-Fever
Rabies
Rift Valley Fever
Salmonellosis
Sheep and Goat Pox Virus
Small Ruminant Lentiviruses
Staphylococcus aureus mastitis
Swine A. pleuropneumoniae
Swine Mycoplasmas (scores for M. hyopneumoniae)
Swine Vesicular Disease
Theileria
Toxoplasmosis
Varroa mite
West Nile Virus
Step 2:
select type of report
Disease & product analysis
Prioritisation model
Gap analysis
Scoring criteria
About types of report
Step 3:
select categories
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Control Tools
Diagnostics availability
Commercial diagnostic kits available worldwide
Diagnostic kits validated by International, European or National Standards
Diagnostic method(s) described by International, European or National standards
Commercial potential for diagnostic kits in Europe
DIVA tests required and/or available
Vaccines availability
Commercial vaccines availability (globally)
Marker vaccines available worldwide
Effectiveness of vaccines / Main shortcomings of current vaccines
Commercial potential for vaccines in Europe
Regulatory and/or policy challenges to approval
Commercial feasibility (e.g manufacturing)
Opportunity for barrier protection
Pharmaceutical availability
Current therapy (curative and preventive)
Future therapy
Commercial potential for pharmaceuticals in Europe
Regulatory and/or policy challenges to approval
Commercial feasibility (e.g manufacturing)
New developments for diagnostic tests
Requirements for diagnostics development
Time to develop new or improved diagnostics
Cost of developing new or improved diagnostics and their validation
Research requirements for new or improved diagnostics
Technology to determine virus freedom in animals
New developments for vaccines
Requirements for vaccines development / main characteristics for improved vaccines
Time to develop new or improved vaccines
Cost of developing new or improved vaccines and their validation
Research requirements for new or improved vaccines
New developments for pharmaceuticals
Requirements for pharmaceuticals development
Time to develop new or improved pharmaceuticals
Cost of developing new or improved pharmaceuticals and their validation
Research requirements for new or improved pharmaceuticals
Disease details
Description and characteristics
Pathogen
Variability of the disease
Stability of the agent/pathogen in the environment
Species involved
Animal infected/carrier/disease
Human infected/disease
Vector cyclical/non-cyclical
Reservoir (animal, environment)
Description of infection & disease in natural hosts
Transmissibility
Pathogenic life cycle stages
Signs/Morbidity
Incubation period
Mortality
Shedding kinetic patterns
Mechanism of pathogenicity
Zoonotic potential
Reported incidence in humans
Risk of occurence in humans, populations at risk, specific risk factors
Symptoms described in humans
Likelihood of spread in humans
Impact on animal welfare and biodiversity
Both disease and prevention/control measures related
Endangered wild species affected or not (estimation for Europe / worldwide)
Slaughter necessity according to EU rules or other regions
Geographical distribution and spread
Current occurence/distribution
Epizootic/endemic- if epidemic frequency of outbreaks
Speed of spatial spread during an outbreak
Transboundary potential of the disease
Route of Transmission
Usual mode of transmission (introduction, means of spread)
Occasional mode of transmission
Conditions that favour spread
Detection and Immune response to infection
Mechanism of host response
Immunological basis of diagnosis
Main means of prevention, detection and control
Sanitary measures
Mechanical and biological control
Diagnostic tools
Vaccines
Therapeutics
Biosecurity measures effective as a preventive measure
Border/trade/movement control sufficient for control
Prevention tools
Surveillance
Past experiences on success (and failures) of prevention, control, eradication in regions outside Europe
Costs of above measures
Disease information from the WOAH
Disease notifiable to the WOAH
WOAH disease card available
WOAH Terrestrial Animal Health Code
WOAH Terrestrial Manual
Socio-economic impact
Zoonosis: impact on affected individuals and/or aggregated DALY figures
Zoonosis: cost of treatment and control of the disease in humans
Direct impact (a) on production
Direct impact (b) cost of private and public control measures
Indirect impact
Trade implications
Impact on international trade/exports from the EU
Impact on EU intra-community trade
Impact on national trade
Links to climate
Seasonal cycle linked to climate
Distribution of disease or vector linked to climate
Outbreaks linked to extreme weather
Sensitivity of disease or vectors to the effects of global climate change (climate/environment/land use)
Main perceived obstacles for effective prevention and control
Main perceived facilitators for effective prevention and control
Global challenges
Antimicrobial resistance (AMR)
Mechanism of action
Conditions that reduce need for antimicrobials
Alternatives to antimicrobials
Impact of AMR on disease control
Established links with AMR in humans
Digital health
Precision technologies available/needed
Data requirements
Data availability
Data standardisation
Climate change
Role of disease control for climate adaptation
Effect of disease (control) on resource use
Effect of disease (control) on emissions and pollution (greenhouse gases, phosphate, nitrate, …)
Preparedness
Syndromic surveillance
Diagnostic platforms
Mathematical modelling
Intervention platforms
Communication strategies
Main critical gaps
Conclusion
Sources of information
Expert group composition
Date of submission by expert group
References
STAR-IDAZ Research Road Maps
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DISEASE KNOWLEDGE - 10 criteria
Speed of spread
Number of livestock species involved
Persistence of the infectious agent in the environment
Risk of spread to susceptible populations
Potential for silent spread
Wildlife reservoir and potential spread
Vector reservoir and potential spread
Variability of the agent
Understanding of fundamental immunology
Host-Pathogen interaction
IMPACT ON ANIMAL HEALTH AND WELFARE - 3 criteria
Disease impact on production
Duration of animal welfare impact
Proportion of animal affected suffering pain/ injury/ distress as a result of the disease
IMPACT ON PUBLIC HEALTH - HUMAN HEALTH - 6 criteria
Impact of occurence on human health
Likelihood of occurence
Impact of occurrence on food safety
Transmissibility (spread from animal to human)
Spread in humans
Bioterrorism potential
IMPACT ON WIDER SOCIETY - 3 criteria
Economic direct impact (including cumulative costs (e.g. Enzoonotic vs Epizootic))
Economic indirect impact (social, market)
Agriterrorism potential
IMPACT ON TRADE - 4 criteria
Impact on international trade due to existing regulations
Impact on EC trade due to existing regulations
Potential for zoning
Impact on security of food supply
CONTROL TOOLS - 3 criteria
Appropriate diagnostics
Appropriate vaccines
Appropriate pharmaceuticals
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Diagnostic tools
Availability
Prevention and control - Differentiation of infected from vaccinated (DIVA)
Strategic reserve
Capacity of production
Affordable
Quality/stability/durability
Sensitivity
Specificity
Reproducibility
Simplicity/ease of use
Speed
Vaccination tools
Commercial availability
Monitoring of infection in a vaccinated population
Strategic reserve
Capacity of production
Affordable
Quality/stability
Safety of vaccines
Efficacy
Immunity
Convenience of use
Pharmaceutical tools
Capacity of production
Availability
Prevention and control
Strategic reserve
Cost
Quality
Safety Animal
Safety Consumer/user concerns
Safety Environment
Resistance
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